Founder & Chief Scientific Officer, Oragenics — Creator of ProBiora3®

The research behind ProBiora3® didn't happen overnight. It began at the Harvard-affiliated Forsyth Institute in Boston, continued at the University of Florida, and spanned more than 35 years of dedicated scientific inquiry into one question: what does a genuinely healthy mouth look like at the microbial level?

Dr. Jeffrey Hillman — a Harvard-trained dentist and microbiologist with over 125 published papers on cavities, periodontal disease, and oral infectious disease — answered that question by isolating the three bacterial strains native to healthy teeth and gums. Those strains became ProBiora3®, the patented blend at the heart of every ProBiora product.

This library is the body of evidence behind that work. Every study here contributed to building, validating, or expanding the science of oral probiotics. Browse by category to explore the research.

Our flagship probiotic formula for complete oral health.

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Backed by years of research and clinical studies.